Pearl AI does not publish a pricing page, which makes its cost one of the most common questions dentists ask about dental AI software. After pulling together third-party directory listings, partner promotions, and published case studies, here is the clearest picture available in 2026 of what Pearl actually costs a single-location practice, a multi-doctor group, and an enterprise DSO — and whether the math holds up against the production lift Pearl reports.
If you want the full feature deep-dive first, start with our Pearl review. This page focuses purely on the money.
Pricing Overview
Pearl sells two flagship products and a handful of add-ons. Each is priced separately, and the company prefers to quote practices through a sales conversation rather than a checkout page. Based on third-party directory listings, Patterson Dental promotional materials, and Pearl's own product pages, here is what the public data shows:
- Second Opinion (real-time radiographic AI) starts around $299 per month on a flat-rate subscription, according to Pearl's Capterra listing, with a free trial available.1
- Practice Intelligence (operational analytics layered on top of Second Opinion) is the more substantial line item. Third-party reviews list it starting at roughly $549 per month (or about $494/month if prepaid annually) per office,2 plus a one-time $500 historical AI analysis fee per office.3
- Setup fees are not published by Pearl, and the third-party figures conflict. The same directory listing that carries the Practice Intelligence prices above states a Second Opinion one-off setup fee of about $500;4 a separate third-party review, reasoning from Patterson Dental's "50% off, save up to $750" promotion, instead infers a standard setup closer to $1,500.17 We lead with the directly stated ~$500 figure and treat the promo-derived ~$1,500 as a high-end estimate — the two differ by roughly 3x, so confirm the current number with Pearl. Setup typically includes back-cataloging historical radiographs so the AI has a baseline for the practice.
- Smart Margin (insurance claim cleanup) and AI-powered insurance verification are quoted custom — there is no published list price.
- Enterprise and DSO pricing is volume-based and negotiated. Pearl reports it was selected by PDS Health across its 1,100+ practices5 and is deploying across Coast Dental's 88 offices6 — deals that are clearly nothing like the single-practice rate card.
For a typical single-location general practice running Second Opinion plus Practice Intelligence, our own budgeting estimate is roughly $700–$900 per month in subscription costs after setup. Solo practices that only want the diagnostic layer can start closer to $300/month. (Those two ranges are TMR estimates built from the sourced $299 and $549 figures above, not quoted bundle prices.)
A note on sourcing: the Second Opinion monthly price comes from a third-party directory rather than Pearl, and the setup figure is an inference from a partner promotion — so treat both as approximate. Pearl's Practice Intelligence monthly and one-time fees come from third-party review listings, not Pearl — the company still routes pricing to a sales conversation. Pricing in dental AI moves quickly; always request a current quote before budgeting.
What's Included in Each Plan
Second Opinion
This is Pearl's core radiographic AI and the product most practices start with. The subscription includes:
- Real-time analysis of bitewings, periapicals, and panoramics — Pearl reports each radiograph is analyzed in 30 seconds or less7
- Detection across caries, calculus, periapical pathology, margin discrepancies, and bone-loss areas
- Color-coded overlays inside a secure browser viewer
- Tooth Parts mapping and patient-friendly comparison views for case presentation
- Exportable patient health reports
- Native integration with 40+ imaging and practice-management platforms, including Dexis, Carestream, Apteryx, Open Dental, and Eaglesoft8
- 24/7 support via phone, email, and chat9
- Historical analysis of existing radiographs at onboarding (covered by the setup fee)
Practice Intelligence
This is the analytics and revenue-recovery layer, and it sits on top of Second Opinion. The subscription includes:
- Continuous scanning of radiographs, treatment plans, and patient records to surface untreated conditions
- Smart call lists sorted by treatment urgency and case value
- AI-prioritized morning huddle agendas
- Historical chart auditing — Pearl reports processing up to 18 months of historical radiographs at onboarding10
- PMS integration for unscheduled-treatment recall workflows
- Operational dashboards for clinician performance and case acceptance trends
Add-Ons
- Smart Margin — automated review of restorative margins for quality control and insurance documentation. Custom quote.
- AI-powered insurance verification — pre-visit benefits checks. Custom quote.
- 3D / CBCT analysis — Pearl says it is the only radiologic AI FDA-cleared to support both 2D and 3D diagnostic workflows.11 Pricing is bundled into enterprise deals.
Costs to Factor In Beyond the Sticker Price
Subscription fees are only part of the picture. A few line items practices should plan for:
- One-time setup fee. A third-party directory listing states a one-off Second Opinion setup fee of about $500, including historical radiograph analysis;4 a separate review infers roughly $1,500 from Patterson's 50%-off promotion.17 The figures conflict by about 3x, so treat setup as an open number to confirm with Pearl — and watch Patterson Dental's promotional cycles, since 50% setup discounts have appeared before.
- Historical AI analysis for Practice Intelligence. Third-party reviews cite a one-time $500 per office fee on top of the monthly subscription, separate from the Second Opinion setup.3
- Imaging platform compatibility check. Pearl integrates with most major imaging systems, but practices on niche or older platforms may need a brief integration scoping call.
- Team training time. Pearl handles installation and onboarding, but the practice still invests staff hours in workflow adjustments — particularly for front-office teams adopting Practice Intelligence call lists.
- Annual vs. monthly billing. Practice Intelligence carries roughly a 10% discount when prepaid annually ($494 vs. $549 in third-party listings).2 Worth the math if cash flow allows.
- Multi-location pricing. If you operate more than one office, ask for a multi-site quote up front — per-location rates typically drop with scale.
- Contract terms. Ask whether Pearl requires a multi-year commitment or offers month-to-month billing, and confirm it in writing — terms can vary by configuration and aren't published.
These aren't surprises so much as line items that get missed when comparing Pearl against tools that quote a single all-in number.



