Here is a fact most dentists don't know about the AI reading their X-rays: some of the biggest names in dental insurance got there first. Guardian began running Overjet's AI inside its claims review back in 2019, and the company has since named MetLife and Humana among its payer partners. So when your practice submits a crown with an Overjet-annotated radiograph, there is a reasonable chance the reviewer on the other end is looking at output from the same underlying technology. That two-sided position — chairside AI for providers, claims AI for payers — is what makes Overjet unlike anything else in dental software.
Overjet competes in the diagnostic AI category with Pearl and VideaHealth, and all three have earned FDA clearances and real clinical followings. But Overjet's ambition is broader than detection overlays: it now spans AI-native imaging software, automated insurance verification, voice-powered clinical documentation, and enterprise analytics, with some of the largest dental support organizations in the country rolling it out across hundreds of locations.
What Is Overjet?
Overjet is a dental AI platform founded in 2018 by computer scientists from MIT and dentists from Harvard, incubated at the Harvard Innovation Labs. CEO Wardah Inam has built the Boston-based company into what is widely described as the best-funded pure-play dental AI business: it has raised more than 130 million dollars across four rounds, most recently a Series C led by March Capital in March 2024 at a reported valuation north of half a billion dollars, with General Catalyst, Insight Partners, and Crosslink Capital among earlier backers.
What began as radiograph analysis has grown into four product pillars:
- Vision AI — FDA-cleared detection and quantification on X-rays: caries, calculus, periapical radiolucencies, and bone-level measurements, rendered as color-coded overlays
- IRIS — a full AI-native imaging suite designed to replace traditional imaging software, not just sit on top of it
- Insurance Verification and claims tools — automated eligibility and benefits checks across 300+ payers, plus ReviewPASS for faster claim-approval confirmation
- Overjet Voice — voice-powered perio charting and clinical documentation, added through the company's acquisition of DentalBee
The distinctive part is the customer list on the other side of the claim. Overjet reported 15 major dental carriers as customers as far back as 2021, covering more than 53 million insured Americans — a figure its later communications put at over 75 million. Guardian was the first national carrier to integrate Overjet into claims processing, and the company's Dental Clarity Network initiative counts MetLife, Humana, and Guardian alongside provider groups like Dental Care Alliance and North American Dental Group as founding partners. No other dental AI company operates at that scale on the payer side.
Key Features
Vision AI: FDA-Cleared Detection and Quantification
Overjet's clinical core is its detection engine. The company earned what it describes as a dental industry first in 2021, when its Dental Assist software was FDA-cleared to measure mesial and distal bone levels on bitewings and periapicals — not just flag disease, but quantify it as a percentage against root length. Caries detection followed in 2022 and was expanded to periapical radiographs in 2023, alongside calculus detection and periapical radiolucency identification. A charting-focused clearance added automated detection of restorations, implants, endodontic treatment, and tooth numbering.
In practice, that means every X-ray gets an annotated read: decay outlined, calculus flagged, bone loss measured in numbers a patient can see. Practices consistently report that the quantified bone-level measurement is the standout — it turns a subjective perio conversation into an objective one, and it standardizes diagnosis across providers, which is precisely why large groups mandate it.
In December 2025 the company announced FDA clearance for CBCT Assist, its tenth clearance by its own count, extending the platform into 3D: automatic segmentation and labeling of anatomy in cone-beam scans, periodontal bone levels in 3D, airway measurements, and tooth-to-nerve or tooth-to-sinus distances for surgical planning.
IRIS: AI-Native Imaging Software
Most dental AI products layer on top of whatever imaging software a practice already runs. IRIS takes the opposite approach: it is a full imaging suite — capture, storage, enhancement, and analysis — with the AI built in. It is sensor-agnostic, works with intraoral cameras and pano machines, keeps images viewable offline, and includes unlimited cloud storage in place of per-gigabyte fees.
The headline capability is image enhancement. Overjet earned an FDA clearance in 2024 for AI-powered enhancement of low-quality radiographs — the company describes itself as the first dental AI platform cleared to enhance images — sharpening blurry or noisy X-rays while preserving diagnostic detail. For groups tired of maintaining on-premise imaging servers, consolidating imaging and AI into one cloud product is a genuinely different pitch than another overlay subscription, and it is the product driving some of Overjet's largest announced rollouts: North American Dental Group across 240+ practices and Mortenson Dental Partners across 147.
Insurance and Claims AI: Both Sides of the Transaction
This is the section that separates Overjet from every other tool in the category — and the reason this review matters for any practice frustrated with verification and claims work.
On the practice side, Overjet's Insurance Verification connects to more than 300 payers (company-reported) through direct data feeds and automated portal retrieval, then returns code-level benefit breakdowns: frequency limits, coverage percentages, downgrades and alternate benefits, missing tooth clauses, and service history. Verifications run automatically days before the appointment, and the company reports that a full day's patient list can be verified in seconds — replacing what it estimates at 20 to 40 front-desk hours per week of phone calls and portal logins. Onboarding is white-glove and, per the company, takes about a week.
On the payer side, insurers use Overjet for utilization review and claims consistency — the company reports its AI cuts administrative review work by as much as 90 percent and speeds claim decisions several-fold. The practice-facing benefit of that payer adoption is alignment: when the provider and the reviewer look at the same objective measurements, documentation disputes narrow. ReviewPASS, offered first to DSO partners, aims to confirm claim approvals for hundreds of common procedures upfront, so patients and providers know where they stand before treatment rather than weeks after submission.
For practices evaluating AI-driven insurance workflows as a category, this dual footprint is Overjet's structural advantage: it is not guessing at what payers want to see on a claim — it powers review on the other side.
Overjet Voice: Documentation Without the Keyboard
Overjet acquired DentalBee to add voice AI, now shipping as Overjet Voice: hands-free perio charting, voice-generated clinical notes, referral letters, and visit summaries that sync with the patient record. It reached general availability in early 2026, and North American Dental Group announced plans to deploy it across 216 locations. Paired with the imaging AI, the pitch is a unified clinical record — diagnosis, documentation, and analytics from one vendor — with structured notes that support cleaner claims and audit-ready records.
DSO and Practice Analytics
Overjet's analytics layer gives multi-location groups visibility from the portfolio level down to the individual provider: treatment patterns, diagnostic consistency, case acceptance, and coaching opportunities. The company reports customers seeing meaningfully higher care acceptance after rollout — its DSO materials cite figures like 25 percent — though, as with any vendor-reported outcome, results vary by practice and depend on how fully teams adopt the workflow. For solo practices, the same engine powers a lighter set of daily-huddle and patient-level insights.
Integrations
Overjet is cloud-based and browser-accessible, integrating with major practice management systems and imaging hardware rather than replacing the PMS. IRIS is deliberately sensor-agnostic, and implementation includes analyzing up to 12 months of historical X-rays so the AI is useful on day one rather than starting from an empty archive. On the revenue-cycle side, the 300+ payer connections are the integration story. One planning note: Overjet publishes less public detail about specific PMS compatibility than some competitors, so confirm your exact stack — especially older on-premise imaging setups — during the demo.
Security and Compliance
Overjet is HIPAA-compliant and holds both HITRUST and SOC 2 certifications — a stronger third-party security posture than most tools in the category publish, and consistent with a company that also has to satisfy insurance-carrier security reviews. Deployment is cloud-based, which keeps PHI off local servers and simplifies multi-site governance.