Software Review

Relu Review (2026)

By The Molar Report|Updated April 5, 2026|4 min read
Our Take
Best ForImplantologists and oral surgeons doing CBCT-guided treatment planning
Key StrengthBest-in-class AI CBCT segmentation with 1-click surgical guide generation
Biggest DrawbackPer-case pricing not publicly listed

What It Is

Relu is a Belgian AI company that has built what is arguably the most impressive automated CBCT segmentation software in dentistry. Their flagship product, Relu Creator, takes a CBCT scan and uses artificial intelligence to segment it into a detailed 3D model -- mandible, maxilla, individual teeth, sinuses, airway, and mandibular canals -- in under 15 minutes. What used to take a trained technician 2-4 hours of manual work now happens automatically in the cloud.

The company has also expanded into Relu Automate for dental lab design automation and Relu Engine, an API that lets other software companies embed Relu's AI segmentation into their own platforms. Partners include Planmeca, Ray, X-Nav, Claronav, and Medialab. When you see "AI-powered segmentation" in another company's product, there's a good chance Relu is the engine underneath.

Both CE marked and FDA 510(k) cleared, Relu operates in a regulatory tier that most dental AI startups haven't reached.

Who It's For

Relu Creator targets implantologists, oral surgeons, orthodontists, and any clinician doing CBCT-guided treatment planning. If you're placing implants and need to plan around the mandibular canal, or you're an orthodontist assessing root positions and airway, Relu turns your CBCT data into actionable 3D models.

The software is also increasingly relevant for practices offering virtual treatment planning consultations. By merging CBCT data with intraoral scans and facial photographs, Relu creates a "virtual patient" that enables comprehensive digital planning and patient communication.

Dental labs using Relu Automate get AI-assisted design for surgical guides, splints, and other prosthetic components -- reducing design time and manual labor.

Key Features

AI CBCT Segmentation: Upload a CBCT scan and receive segmented 3D models of all anatomical structures in under 15 minutes. The AI handles mandible, maxilla, individual tooth segmentation, sinus boundaries, airway volume, and mandibular canal tracing. Accuracy is clinically validated.

Multi-Scan Fusion: Automatically aligns and merges CBCT scans, digital impressions (intraoral scans), and facial scans into a single virtual patient. This fusion is the foundation for comprehensive digital treatment planning.

Surgical Guide Design: Relu's latest innovation is 1-click surgical guide generation -- from CBCT to printable surgical implant guide with minimal manual intervention. This collapses what used to be a multi-step, multi-software workflow into a single process.

Relu Engine (API): For software developers and companies that want to embed Relu's AI segmentation into their own platforms. This B2B play has made Relu the backbone of several major imaging software products.

Relu Automate: AI-powered design automation for dental labs, handling surgical guides, dental splints, and chairside lab workflows.

Pros

  • Strong AI CBCT segmentation -- under 15 minutes versus hours of manual work
  • FDA 510(k) cleared and CE marked for regulated clinical use
  • Pay-per-case pricing eliminates subscription waste
  • Multi-scan fusion creates a comprehensive virtual patient
  • Powers other major imaging platforms via Relu Engine API
  • 1-click surgical guide design is genuinely revolutionary
  • Used by 4,000+ dentists with strong clinical validation

Cons

  • Per-case pricing not publicly listed, making cost planning difficult
  • Requires high-quality CBCT scans -- garbage in, garbage out still applies
  • Learning curve for practitioners unfamiliar with 3D treatment planning workflows
  • European company -- support hours may not align with US time zones
  • Not a standalone treatment planning platform -- works alongside other software
  • The technology moves fast, requiring ongoing learning to stay current

What We Like and What We Don't

What Works
  • Best-in-class AI CBCT segmentation in under 15 minutes
  • FDA 510(k) cleared and CE marked
  • Pay-per-case pricing eliminates subscription waste
  • 1-click surgical guide design is revolutionary
  • Powers major imaging platforms via API partnerships
What Doesn't
  • Per-case pricing not publicly listed
  • Requires high-quality CBCT input scans
  • European company with potential support timezone gaps
  • Not a standalone planning platform
  • Learning curve for 3D workflow newcomers

Who This Is For (and Who Should Look Elsewhere)

Relu Is a Strong Fit If You...

  • Best-in-class AI CBCT segmentation in under 15 minutes
  • FDA 510(k) cleared and CE marked
  • Pay-per-case pricing eliminates subscription waste
  • 1-click surgical guide design is revolutionary
  • Powers major imaging platforms via API partnerships

You Should Look Elsewhere If You...

  • Per-case pricing not publicly listed
  • Requires high-quality CBCT input scans
  • European company with potential support timezone gaps
  • Not a standalone planning platform
  • Learning curve for 3D workflow newcomers

How It Compares

Relu vs. Top AlternativesSee full comparisons →
ReluPearlDentalMonitoring
TMR Score8.89.09.0
ArchitectureCloud-basedCloud-basedcloud-native
Starting PriceCustomPer locationCustom
Best ForImplantologists and oral surgeons doing CBCT-guided treatment planningAny practice that wants AI-assisted radiograph analysis to catch missed pathology and improve case acceptance. Especially valuable for DSOs standardizing clinical quality across locations.Orthodontic practices and DSOs looking to reduce in-office visits by 45% while maintaining clinical control through AI-powered remote monitoring of aligner and braces treatments across all brands.

The Bottom Line

Our recommendation: If Relu matches your practice profile, put it on your shortlist. Visit their site and make your decision based on the numbers and the fit.

This review is based on independent research. Read our methodology. Something look off? Let us know.